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Abdominal Transplant Fellowship »  Fellows »  Past Fellows »  Garrett R. Roll, M.D.
Garrett R. Roll, M.D., FACS

Garrett R. Roll, M.D., FACS

Associate Professor of Surgery
Division of Transplant Surgery

Contact Information

Academic Office
(415) 353-8725
garrett.roll@ucsf.edu
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Boston College, BS, Finance, 1995-1999
Brandeis University, Post Baccalaureate, Premedical, 1999-2001
Temple University School of Medicine, MD, 2001-2005

  • University of California, San Francisco, General Surgery, 2005-2012
  • UCSF Department of GI Hepatology Research Fellowship
  • University of California, San Francisco, Abdominal Transplant Surgery, 2012-2014
  • Senior international Fellow in liver transplant and retrieval, Queen Elizabeth Hospital, Birmingham, England
  • American Board of Surgery, General Surgery
  • Transplantation
  • HBP surgery
  • Ascites
  • Bile Duct Cancer (Cholangiocarcinoma)
  • Bile Duct Injuries
  • Bile Duct Strictures
  • Bridging Therapies to Downstage HCC in Liver Transplant Setting
  • Choledochal Cysts
  • Deceased Donor Organ Utilization
  • Gallbladder Cancer
  • Hepatocellular Carcinoma (Primary Liver Cancer)
  • Kidney Transplantation
  • Laparoscopic Donor Nephrectomy
  • Liver Biopsy
  • Liver Cysts
  • Liver Metastases (Secondary Liver Cancer)
  • Liver Resection
  • Liver Transplantation
  • Living Donor Kidney Transplantation
  • Living Donor Liver Transplantation
  • Normothetic Machine Liver Perfusion
  • Organ Donation of Cardiovascular Death
  • Pancreas Transplantation
  • Pediatric Kidney Transplantation
  • Pediatric Liver Transplantation
  • Portal Hypertension
  • Cell therapy with hepatocytes and hepatocyte-like cells derived from stem cells.
  • Normothetic machine liver perfusion
  • Role of miRNA in liver regeneration

Dr. Roll is a general surgeon specializing in abdominal organ transplantation. He completed both general surgery training and the abdominal organ transplant fellowship at the University of California San Francisco. 

During his training, Dr. Roll spent 2 years in Dr. Holger Willenbring's laboratory investigating stem cell biology in the context of liver cell therapy, as well as normal and pathologic liver regeneration. His research concentrated on the use of hepatocyte-like cells derived from stem cells to be used in liver cell therapy. In particular, Dr. Roll investigated the regenerative capabilities of hepatocytes derived from induced pluripotent stem (iPS) cells. They used a genetically deficient mouse model of liver disease as a way to test the functional capabilities of these cells after transplantation. They were able to demonstrate that the profound proliferative capabilities of adult hepatocytes are retained by hepatocytes derived from iPS cells, and transplanting these cells rescued mice with liver failure. Dr. Roll also investigated the role of miRNA in liver regeneration, and the rejection of transplanted hepatocytes and hepatocyte-like cells. The principles of his research will remain valuable in liver and pancreas cell therapy translational science for years.

After fellowship Dr. Roll moved to England to become a Senior International Fellow in Liver Transplant and Multi Organ Procurement at Queen Elizabeth Hospital, Birmingham, one of the busiest liver transplant departments in the United Kingdom. There he gained valuable experience in the blossoming field of normothermic machine liver perfusion prior to returning to UCSF. 

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MOST RECENT PUBLICATIONS FROM A TOTAL OF 91
Data provided by UCSF Profiles, powered by CTSI
  1. Roll GR, Spiro M, Raptis DA, Jalal A, Yan CT, Olthoff KM, Caicedo JC, Lee KW, Yagi S, Cattral MS, Soin AS, ERAS4OLT.org Working Group. Which recipient pretransplant factors, such as MELD, renal function, sarcopenia, and recent sepsis influence suitability for and outcome after living donor liver transplantation? - A systematic review of the literature and expert panel recommendations. Clin Transplant. 2022 Mar 27; e14656. View in PubMed
  2. Whelan AM, Johansen KL, Copeland T, McCulloch CE, Nallapothula D, Lee BK, Roll GR, Weir MR, Adey DB, Ku E. Kidney transplant candidacy evaluation and waitlisting practices in the US and their association with access to transplantation. Am J Transplant. 2022 Mar 15. View in PubMed
  3. Roll GR, Cooper M, Verbesey J, Veale JL, Ronin M, Irish W, Waterman AD, Flechner SM, Leeser DB. Risk aversion in the use of complex kidneys in paired exchange programs: Opportunities for even more transplants? Am J Transplant. 2022 Feb 18. View in PubMed
  4. Roll GR, Hirose R. Toward a more efficient organ placement system (and defeating FOMO). Am J Transplant. 2022 Feb 18. View in PubMed
  5. Markmann JF, Abouljoud MS, Ghobrial RM, Bhati CS, Pelletier SJ, Lu AD, Ottmann S, Klair T, Eymard C, Roll GR, Magliocca J, Pruett TL, Reyes J, Black SM, Marsh CL, Schnickel G, Kinkhabwala M, Florman SS, Merani S, Demetris AJ, Kimura S, Rizzari M, Saharia A, Levy M, Agarwal A, Cigarroa FG, Eason JD, Syed S, Washburn WK, Parekh J, Moon J, Maskin A, Yeh H, Vagefi PA, MacConmara MP. Impact of Portable Normothermic Blood-Based Machine Perfusion on Outcomes of Liver Transplant: The OCS Liver PROTECT Randomized Clinical Trial. JAMA Surg. 2022 Mar 01; 157(3):189-198. View in PubMed
  6. View All Publications

 

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