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Abdominal Transplant Fellowship »  Faculty »  Transplant Surgeons »  James M. Gardner, M.D., Ph.D.
James M. Gardner, M.D., Ph.D.

James M. Gardner, M.D., Ph.D.

Assistant Professor of Surgery
Division of Transplant Surgery


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Harvard University, B.A., Biochemical Sciences, 2002
University of California San Francisco, M.D., Ph.D. 2012
  • University of California San Francisco, Intern, General Surgery, 2012-2013
  • University of California San Francisco, Resident, General Surgery, 2013-2016
  • University of California San Francisco, Chief Resident, General Surgery, 2016-2017
  • University of California San Francisco, Abdominal Transplant Clinical Fellow, 2017-2019
  • American Board of Surgery, General Surgery
  • UCSF Department of Surgery
  • UCSF Division of Transplant Surgery
  • UCSF Diabetes Center
  • Ascites
  • Bile Duct Cancer (Cholangiocarcinoma)
  • Bile Duct Injuries
  • Bile Duct Strictures
  • Bridging Therapies to Downstage HCC in Liver Transplant Setting
  • Choledochal Cysts
  • Deceased Donor Organ Utilization
  • Gallbladder Cancer
  • Hepatocellular Carcinoma (Primary Liver Cancer)
  • Kidney Transplantation
  • Laparoscopic Donor Nephrectomy
  • Liver Biopsy
  • Liver Cysts
  • Liver Metastases (Secondary Liver Cancer)
  • Liver Resection
  • Liver Transplantation
  • Living Donor Kidney Transplantation
  • Living Donor Liver Transplantation
  • Normothetic Machine Liver Perfusion
  • Organ Donation of Cardiovascular Death
  • Pancreas Transplantation
  • Pediatric Kidney Transplantation
  • Pediatric Liver Transplantation
  • Portal Hypertension
  • Immune tolerance
  • Autoimmmune diabetes
  • Transplant surgery
  • Spanish

James M. Gardner, M.D., Ph.D. is an Assistant Professor in the Division of Transplant Surgery and a transplant surgeon who performs kidney, liver and pancreas transplants for both adults and children. 

Dr. Gardner earned his B.A. from Harvard University in Biochemical Sciences and his M.D. and Ph.D. degrees from UCSF. He then completed his General Surgery Residency at UCSF followed by a two-year clinical fellowship in Transplant Surgery.

Recently, Dr. Gardner was awarded an appointment to the prestigious Physician-Scientist Scholar Program (PSSP), only one of which is given per year among all departments in the School of Medicine, and provides direct research funding to support early-career scientists. Dr. Gardner is the first surgeon to receive this award, part of the UCSF Sandler Fellows Program. 

  Award  
  Confired By    
  Date    
  • Sander PSSP Grant
  • UCSF Dean's Office
  • 2019 - 2024
  • Sandler PSSP Grant
  • UCSF Dean's Office
  • 2019 - 2024
  • ASTS-Astellas Fellowship in Transplantation Grant
  • American Society of Transplant Surgeons
  • 2017 - 2019
  • Nusz Achievement Award
  • UCSF Department of Surgery
  • 2017 - 2017
  • Schecter Award for Senior Trauma Fellow
  • UCSF Division of Trauma and Critical Care
  • 2016 - 2016
  • ED Surgical Consultant of the Year
  • UCSF Emergency Medicine
  • 2016 - 2016
  • Dr. Gardner's research is focused on the mechanisms regulating self-tolerance in the adaptive immune system, and translating these findings into relevant therapeutics for inducing and maintaining donor-specific tolerance. In mentored collaboration with the Mark Anderson lab at the UCSF Diabetes Center, Dr. Gardner's studies focus on a gene called the Autoimmune Regulator, or Aire, which is a key regulator of central tolerance. Dr. Gardner and Dr. Anderson have defined a novel population of extrathymic Aire-expressing cells (eTACs), and their work focuses on the role of this population in autoimmunity and tolerance.
    MOST RECENT PUBLICATIONS FROM A TOTAL OF 20
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    1. Wang J, Lareau CA, Bautista JL, Gupta AR, Sandor K, Germino J, Yin Y, Arvedson MP, Reeder GC, Cramer NT, Xie F, Ntranos V, Satpathy AT, Anderson MS, Gardner JM. Single-cell multiomics defines tolerogenic extrathymic Aire-expressing populations with unique homology to thymic epithelium. Sci Immunol. 2021 Nov 12; 6(65):eabl5053. View in PubMed
    2. Gillis-Buck E, Miller H, Sirota M, Sanders SJ, Ntranos V, Anderson MS, Gardner JM, MacKenzie TC. Extrathymic Aire-expressing cells support maternal-fetal tolerance. Sci Immunol. 2021 Jul 16; 6(61). View in PubMed
    3. Warshauer JT, Belk JA, Chan AY, Wang J, Gupta AR, Shi Q, Skartsis N, Peng Y, Phipps JD, Acenas D, Smith JA, Tamaki SJ, Tang Q, Gardner JM, Satpathy AT, Anderson MS. A human mutation in STAT3 promotes type 1 diabetes through a defect in CD8+ T cell tolerance. J Exp Med. 2021 Aug 02; 218(8). View in PubMed
    4. Dixon W, Feng S, Gardner J. Transplantation From Older Donors: Can Senolytics Turn Back the Clock? Transplantation. 2021 04 01; 105(4):681-682. View in PubMed
    5. Bautista JL, Cramer NT, Miller CN, Chavez J, Berrios DI, Byrnes LE, Germino J, Ntranos V, Sneddon JB, Burt TD, Gardner JM, Ye CJ, Anderson MS, Parent AV. Single-cell transcriptional profiling of human thymic stroma uncovers novel cellular heterogeneity in the thymic medulla. Nat Commun. 2021 02 17; 12(1):1096. View in PubMed
    6. View All Publications
    1. Gardner et al., American Transplant Congress, 2015. Outcomes in a new category of Pancreas-After-Islet Transplantation.
    2. Gardner et al., UCSF Surgery Resident Research Symposium, 2013-2016. Extrathymic Aire-Expressing Cells in Immune Tolerance and Transplantation.
    3. Gardner et al., International Pancreas and Islet Transplant Association 2013. Outcomes in a new category of Pancreas-After-Islet Transplantation.
    4. Gardner et al., Children?s Diabetes Foundation of the North Bay Annual Retreat, 2010. Novel Approaches for Preventing and Treating Juvenile Diabetes: What?s on the Horizon?
    5. Gardner et al., Kyoto T Cell Conference 2009. Extrathymic Aire-Expressing Cells and the Maintenance of Immunologic Tolerance.
    6. Gardner et al., American Diabetes Association Tour de Cure Donors? Evening, 2008. New approaches to Preventing and Treating Autoimmune Diabetes.
    7. Gardner et al., UCSF/UCB 2008 Immunology Retreat. Phenotypic and Functional Characterization of Extrathymic Aire-Expressing Cells.
    1. Gardner JM, Anderson MS. The Mouse Model of Autoimmune Polyglandular Syndrome Type I. Immunoendocrinology: Scientific and Clinical Aspects. 1st edition. Ed. Eisenbarth G. (New York: Humana Press, 2011.)

     

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