Abdominal Transplant Fellowship »  Faculty »  Peter G. Stock, M.D., Ph.D.

Peter G. Stock, M.D., Ph.D.

Professor of Surgery
Surgical Director, Kidney and Pancreas Transplant Program
Surgical Director, Pediatric Renal Transplant Program
Co-Director, Pancreatic Islet Cell Transplant Program
Chair, Department of Surgery Research Committee

Contact Information

Academic Office
(415) 353-8617
peter.stock@ucsfmedctr.org

Appointments
(415) 353-1888 Liver
(415) 353-1551 Kidney and Pancreas

Education

  • University of Illinois, Urbana, IL, B.S., Biology, 1974-78
  • University of Illinois, Chicago, IL, M.D., Medicine, 1978-82
  • University of Minnesota, Minneapolis, MN, Ph.D., Surgery, 1985-92

Residencies

  • University of Minnesota, Intern, General Surgery, 1982-83
  • University of Minnesota, Resident, General Surgery, 1983-90

Fellowships

  • University of California, San Francisco, Fellow, Transplant Surgery, 1990-92

Board Certifications

  • American Board of Surgery, 1991

Clinical Expertise

  • Bile Duct Injuries
  • Bile Duct Strictures
  • Cholangiocarcinoma (Bile Duct Cancer)
  • Choledochal Cyst Disease
  • Dialysis Access
  • End-Stage Kidney Disease
  • Fulminant Hepatic Failure
  • Hepatitis B
  • Hepatitis C
  • Hepatocellular Carcinoma (Liver Cancer)
  • Kidney and LIver Transplantation in HIV Patients
  • Kidney Transplantation
  • Liver Transplantation
  • Living Donor Kidney Transplantation
  • Living Donor Liver Transplantation
  • Pancreas Transplantation
  • Pancreatic Islet Cell Transplantation
  • Pediatric Kidney Transplantation
  • Pediatric Liver Transplantation
  • Polycystic Kidney Disease
  • Polycystic Liver Disease
  • Portal Hypertension

Research Interests

  • Induction of transplantation tolerance to block alloimmunity and recurrent autoimmunity following pancreatic islet transplantation
  • Safety and efficacy of solid organ transplantation in people with HIV

Biography

Peter G. Stock, M.D., Ph.D. is Professor of Surgery at UCSF, Surgical Director of the Pediatric Renal Transplantation Program and Surgical Director of the Pancreas Transplant Program. He was trained at the University of Minnesota, completing a surgical residency before coming to UCSF for a transplant fellowship. He joined the UCSF faculty in 1992.  

Recently, a clincial investigation on which Dr. Stock served as principal investigator led the passage of the Hope Act lifting the ban on research for transplanting organs between HIV-positive donors and recipients.

Highly respected by his peers, Dr. Stock was named to the list of U.S. News "Top Doctors," which denotes the top 10% of physicians within a region practicing a given specialty. He is a frequent presenter on issues related to transplantation and immunosuppression, and holds membership in numerous professional and honorary societies. Dr. Stock specializes in liver, kidney and pancreas transplantation.

Awards & Honors

  • James IVth Fellowship Award 2000 James IVth Fellowship Award, US Representative, 2000 US Representative
  • Faculty Fellowship Award 1993 Faculty Fellowship Award, American College of Surgeons, 1993 American College of Surgeons
  • Sandoz Fellowship Award 1991 Sandoz Fellowship Award, American Society of Transplant Surgeons, 1991 American Society of Transplant Surgeons
  • David Gaviser Award, Outstanding Surgical Research 1989 David Gaviser Award, Outstanding Surgical Research, University of Minnesota, Minneapolis, MN, 1989 University of Minnesota, Minneapolis, MN
  • Outstanding Surgical Resident Teaching Award 1989 Outstanding Surgical Resident Teaching Award, Department of Surgery, University of Minnesota, Minneapolis, MN, 1989 Department of Surgery, University of Minnesota, Minneapolis, MN
  • Outstanding Research Award, Senior Medical Student 1982 Outstanding Research Award, Senior Medical Student, University of Illinois, Chicago, IL, 1982 University of Illinois, Chicago, IL
  • Alpha Omega Alpha 1981 Alpha Omega Alpha, University of Illinois, Chicago, IL, 1981 University of Illinois, Chicago, IL
  • Magna Cum Laude, Honors in Biology with High Distinction 1978 Magna Cum Laude, Honors in Biology with High Distinction, University of Illinois, Urbana, IL, 1978 University of Illinois, Urbana, IL
  • Phi Beta Kappa 1978 Phi Beta Kappa, University of Illinois, Urbana, IL, 1978 University of Illinois, Urbana, IL
View all

Research Overview

Pancreatic Islet Transplantation
The translational research in the field of pancreatic islets revolves around clinical trials of the safety and efficacy of islet transplantation in patients with Type I diabetes. The clinical trials are funded by the National Institutes of Health (NIH) and the Juvenile Diabetes Research Foundation (JDRF). These clinical trials focus on novel immunosuppressive strategies that utilize co-stimulatory blockade to prevent the immune response against pancreatic islets with a regimen that is not toxic to kidneys or beta cells.

Related research involves improving the techniques required for isolating pancreatic islets from the pancreas, which is being conducted in a fully compliant GMP laboratory facility. The study of the alloimmune and autoimmune response following islet transplantation will be conducted to determine the efficacy of the immunosuppressive strategies. Further translational studies will include methods of expanding the source of beta cells, using direct proliferation, as well as manipulation of precursor cells localized in the adult pancreas. We are currently funded (PI) for a translational grant from California Institute of Regenerative Medicine (CIRM) to bring embryonic stem cell-derived beta cells to a clinical trial.

Solid Organ Transplantation in People with HIV
With the advent of highly active anti-retroviral therapy (HAART), HIV has been a chronic disease. People with HIV are no longer dying from progression of HIV to AIDS, but rather as a result of end stage live disease (viral hepatitis co-infection) and kidney disease (HIV nephropathy). Our laboratory heads up the large NIH-sponsored national multicenter trial which is studying the safety and efficacy of solid organ transplantation in people with HIV. Translational research is exploring the impact of HIV on organ function and the impact of immunosuppression on the immune response against HIV and associated copathogens.

Mentored Research Residents

ResidentYearsGrant or Funding Source
Jack Harbell, M.D. 07/2011 – 06/2013 SUS/Ethicon Resident Research Scholarship
James Tong, M.D. 2007-2009
Jonathan Carter, M.D. 2004-2006
Kenzo Hirose, M.D. 2003-2006
Mounir Hajjar, M.D. 2000-2002
Robert W. O'Rourke, M.D. 1997-2000
George J. Chang, MD, MS, FACS, FASCRS 1998-2001
Sang-Mo Kang, M.D. 1995-1998
Robert W. Osorio, M.D., FACS 1992-1995

Clinical Trials

 

Featured Publications

From a total of 173 publications
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